Amelioration effects against N-nitrosodiethylamine and CCl4-induced hepatocarcinogenesis in Swiss albino rats by whole plant extract of Achyranthes aspera
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منابع مشابه
Exploring the Protective Effects of Abrus precatorius in HepG2 and N-Nitrosodiethylamine-Induced Hepatocellular Carcinoma in Swiss Albino Rats
This study was designed to explore the protective effects of Abrus precatorius L. (Leguminosae) (AP) in HepG2 cells and N-nitrosodiethylamine (NDEA) induced hepatocellular carcinoma in Swiss albino rats. The effects of aqueous/ethanolic (50%) extract of AP on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in NDEA ...
متن کاملDiuretic activity of whole plant extract of Achyranthes aspera Linn
Achyranthes aspera Linn (Amaranthaceae), commonly known as Apamarga in Ayurveda and is found as a weed that has been traditionally used for a number of ailments. The plant is indigenously used as diuretic, spermicidal, anti-allergic, cardiovascular, nephroprotective, antiparasitic, hypoglyceamic, analgesic and antipyretic. In the present study the methanolic extract of whole plant of Achyranthe...
متن کاملProtective effect of Genistein against N-nitrosodiethylamine (NDEA)-induced hepatotoxicity in Swiss albino rats
In the present study, we studied the effect of Genistein against the hepatotoxicity induced by N-nitrosodiethylamine (NDEA). NDEA is present in almost all kinds of food stuff and has been reported to be a hepatocarcinogen. The male rats were exposed to NDEA (0.1 mg/mL) dissolved in drinking water separately and along with 25, 50, 100 mg/mL of Genistein for 21 days. The activities of serum gluta...
متن کاملexploring the protective effects of abrus precatorius in hepg2 and n-nitrosodiethylamine-induced hepatocellular carcinoma in swiss albino rats
this study was designed to explore the protective effects of abrus precatorius l. (leguminosae) (ap) in hepg2 cells and n-nitrosodiethylamine (ndea) induced hepatocellular carcinoma in swiss albino rats. the effects of aqueous/ethanolic (50%) extract of ap on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in ndea (200 mg/kg and ccl4, 3 m...
متن کاملPost-treatment effects of Alstonia scholaris extract against radiation-induced biochemical alterations in Swiss albino mice
Background: This study has been undertaken to find out the possible radioprotective potential of the Alstonia scholaris extract (ASE). Materials and Methods: For experimental study, healthy Swiss albino male mice were selected from an inbred colony and divided in four groups. Group I (normal) did not receive any treatment. Group II was orally supplemented ASE once daily at the dose of ...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmacology
سال: 2010
ISSN: 0253-7613
DOI: 10.4103/0253-7613.71921